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Essais expérimentaux avec des OGM (autres que les plantes)

Dissémination volontaire en Belgique d'OGM autres que des plantes supérieures à toute autre fin que leur mise sur le marché (par ex. essais cliniques avec produits médicinaux génétiquement modifiés) - Soumis dans le cadre de la Partie B de l'Arrêté Royal du 21 février 2005
 
Le Belgian Biosafety Server contient une base de données fournissant les informations complémentaires suivantes pour chaque OGM:

  • Description de la dissémination volontaire (sur base des données obtenues dans le dossier public)
  • Informations relatives à la procédure de décision (avis scientifiques, décisions finales)
  • Le "résumé de notification" (SNIF)
  • Information à destination du public rédigée par le notifiant
  • Lignes directrices pertinentes
  • Autres informations pertinentes
Réf. Notifiant OGM Avis du Conseil État des lieux
B/BE/21/BVW3 Prevail Therapeutics

Replication-incompetent adeno-associated virus, AAV9, lacking all AAV viral genes and encoding for the human Progranulin (GRN) gene

Pas d'application
En cours
​B/BE/21/BVW2 ​Larissa consortium and Wageningen Bioveterinary Research

Live-attenuated vaccine

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(06-08-2021)
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B/BE/20/BVW6 Pfizer

Recombinant non-replicating adeno-associated viral vector (AAV2/6) containing a codon-optimised version of the human Factor VIII gene

Pas d'application
Retiré par le notifiant
B/BE/20/BVW5 Nouscom srl

Recombinant GAd20 Gorilla adenovirus and Recombinant vaccinia virus Ankara (MVA) that contain the information to produce patient-specific cancer 'neoantigens' for treatment of skin and lung cancer

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(11-02-2021)
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B/BE/20/BVW4 Pfi​zer

Recombinant AAV vector lacking viral genes and containing a gene encoding a shortened, but functional variant of the human dystrophin gene for treatment of Duchenne Muscular Dystrophy

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(05-02-2021)
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B/BE/20/BVW3 Transgene

Replicative oncolytic vaccinia virus with deletion of the viral thymidine kinase and ribonucleotide reductase genes, and addition of genes encoding for the human granulocyte-macrophage colony-stimulating factor cytokine and for a monoclonal antibody targeting the Cytotoxic T-Lymphocyte-Antigen 4

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(20-10-2020)
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B/BE/20/BVW2 Vaccitech Ltd

Recombinant replication-incompetent chimpanzee-derived adenovirus, and recombinant modified vaccinia virus Ankara vector (MVA), modified with Human Papillomavirus (HPV) surface antigens

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(05-06-2020)
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B/BE/19/BVW4 Merck Sharp & Dohme

Recombinant Vesicular Stomatitis Virus (rVSV) in which the gene coding for the VSV glycoprotein G has been deleted and replaced with the gene encoding the Zaire Ebola virus (ZEBOV) glycoprotein

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(17-09-2019)
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B/BE/19/BVW3 Amgen Ltd

Herpes simplex virus 1 (HSV-1) with gene expressing granulocyte-macrophage colony-stimulating factor (GH-CSF) and deletion of 2 HSV-1 genes

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(13-05-2019)
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B/BE/19/BVW2 BioMarin Pharmaceutical Inc.

Recombinant Adeno-associated virus vector with gene cassette expressing human factor VIII

Download
(24-05-2019)
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B/BE/18/BVW9 GSK Biologicals SA

Recombinant chimpanzee-derived group C adenovirus expressing three proteins from the Respiratory Syncytial Virus (RSV)

Download
(22-01-2019)
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B/BE/18/BVW7 uniQure Bioipharma BV

Recombinant adeno associated viral vector containing a derivative of human coagulation factor IX cDNA

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(11-12-2018)
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B/BE/18/BVW6 AveXis, Inc.

Recombinant adeno-associated virus serotype 2/9 (AAV2/9) containing the cDNA of the human SMN (Survival Motor Neuron) gene

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(07-01-2019)
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B/BE/18/BVW5 Intrexon

Lactococcus lactis genetically modified to produce human interleukin-10 and proinsulin

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(13-09-2018)
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B/BE/18/BVW4 GSK Biologicals SA

Recombinant replication-defective simian (chimpanzee-derived) group C adenovirus, and recombinant modified vaccinia virus Ankara vector (MVA)

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(01-10-2018)
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B/BE/18/BVW3 Oragenics

Lactococcus lactis expressing human Trefoil Factor 1 (hTFF1)

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(11-09-2018)
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B/BE/18/BVW2 University Antwerp, Belgium

Novel live attenuated serotype 2 oral poliovirus vaccines (nOPV2) candidates

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(10-08-2018)
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B/BE/18/BVW1 Transgene S.A.

Replicative oncolytic vaccinia virus with deletion of the viral thymidine kinase and ribonucleotide reductase genes, and insertion of the chimeric yeast FCU1 suicide gene

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(03-07-2018)
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B/BE/17/BVW2 Amgen Ltd

Herpes simplex virus 1 (HSV-1) with gene expressing granulocyte-macrophage colony-stimulating factor (GH-CSF) and deletion of 2 HSV-1 genes

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(27-09-2017)
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B/BE/17/BVW1 Transgene S.A.

Modified Vaccinia virus Ankara (MVA) with sequences coding for human mucine 1 (MUC1) antigen and interleukin-2 (IL2)

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(05-09-2017)
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B/BE/16/BVW1 Amgen Ltd

Herpes simplex virus 1 (HSV-1) with gene expressing granulocyte-macrophage colony-stimulating factor (GH-CSF) and deletion of 2 HSV-1 genes

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(13-12-2016)
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B/BE/15/BVW2 Amgen Ltd

Herpes simplex virus 1 (HSV-1) with gene expressing granulocyte-macrophage colony-stimulating factor (GH-CSF) and deletion of 2 HSV-1 genes

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(12-01-2016)
Clôturé
B/BE/15/BVW1 Amgen Ltd

Herpes simplex virus 1 (HSV-1) with gene expressing granulocyte-macrophage colony-stimulating factor (GH-CSF) and deletion of 2 HSV-1 genes

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(12-10-2015)
Clôturé
B/BE/14/BVW1 Amgen Ltd

Herpes simplex virus 1 (HSV-1) with gene expressing granulocyte-macrophage colony-stimulating factor (GH-CSF) and deletion of 2 HSV-1 genes

Download
(24-02-2015)
Clôturé
B/BE/12/BVW2 Celladon

Recombinant Adeno-associated virus (rAAV) expressing SERCA2a enzym

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(23-01-2013)
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B/BE/12/BVW1 Theravectys

Two recombinant non-pathogenic, non-replicative Lentiviruses for therapeuthic vaccination of HIV infected patients

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(11-09-2012)
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B/BE/11/V3 Laboratorios Hipra

Recombinant Actinobacillus pleuropneumoniae with modified virulence factors

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(16-04-2012)
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B/BE/11/BVW2 Bn Immuno Therapeutics

Recombinant Vaccinia virus and Fowlpox virus expressing PSA and immunological costimulatory molecules

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(07-08-2012)
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B/BE/11/BVW1 Transgene

Recombinant Vaccinia virus expressing MUC1 antigen and hIL-2

Download
(30-09-2011)
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B/BE/09/BVW1 Roche

Recombinant Vaccinia virus expressing hIL-2 and proteins of HPV virus

Download
(09-09-2009)
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B/BE/08/BVW1 MedImmune

Recombinant bovine Parainfluenza virus with genes of human Parainfluenza virus and Respiratory syncitial virus

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(18-06-2009)
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B/BE/07/BVW3 GENimmune

Recombinant Vaccinia virus with gene of Hepatitis B virus

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(07-03-2008)
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B/BE/07/BVW1 Actogenix

Recombinant Lactococcus lactis expressing hIL-10

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(18-01-2008)
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B/BE/04/BV1 Pfizer Animal

Recombinant feline herpes virus

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(15-07-2005)
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B/BE/03/B3 Transgene

Human adenovirus serotype 5 deleted in E1 and E3

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(05-07-2004)
Download
(26-03-2004)
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